Natalia Kutsevol

Natalia Kutsevol

Vice Dean (Research)

Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Junior Researcher
Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Senior Researcher
Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

The head of team «Branched polymers and nanosystems”
Taras Shevchenko national University of Kyiv, Kyiv (Ukraine)

Leading Researcher
Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Vice Dean (Research), Leading researcher
Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)


Preparatory cycle
Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Master degree in Polymer chemistry
Taras Shevchenko National University of Kiev, Kyiv (Ukraine)

Taras Shevchenko National University of Kyiv, Kyiv (Ukraine)

Senior researcher
Taras Shevchenko National University of Kiev, Kyiv (Ukraine)

Taras Shevchenko National University of Kiev, Kyiv (Ukraine)

Doctor of Chemical Science
Taras Shevchenko National University of Kiev, Kyiv (Ukraine) 

Branched polymers, pH and thermosensitive nanosystems for biomedical application

Research Fields:
Biology & Biochemistry
Clinical Medicine

Previous and Current Research

We are focused on fundamental aspects of synthesis and characterization of branched uncharged polymers, polyelectrolytes and stimuli responsible branched polymers in solution as well as hydrogels and nanosystems synthesized in situ into these polymer matrices. We study the response of these complicated systems towards external stimuli ( pH, T ...) and their applications mainly in biomaterials or drug delivery fields.

Branched polymer matrices have various chemical nature and internal structure, higher local concentration of functional groups in comparison with their linear analogue, and they can be very efficient for designing of optimized nanocarriers-nanosystems for medical applications and for water treatment. We are working in collaboration with physicists and biologists.

Figure 1. Nanosystems, synthesized into stimuli responsible polymer matrices of varios atchitecture and internal structure.

Nanosystems for Photodynamic Therapy

Before treatment

After treatment

Hybrid Hydrogels as promising wound dressing




  • Institute  Charles Sadron,Strasbourg, France  (Dr. Michel Rawiso)
  • Kavetsky Institute of  Experimental Pathology, Oncology and Radiobiology, NASU  (Academician V.F. Chekhun)
  • Belarussian State University  (Dr. Vladimior Zorin)
  • Iv.-Frankivsk National Medical University (Prof. Krisa)
  • B.I. Verkin Institute for Low Temperature Physics and nd Engineering, NASU (Corr. Member  V.O. Karatchevtsev)
  • ISMA NASU Bogomoletz Institute of Physiology
  • Clemson University, South Carolina, US
2005-2006  NATO grant ESCCBR/NUKR.CLG 981343
2004-2006 Ukrainian-French project  DNIPRO
2011-2012 NATO grant ESC(2010)0064 CBR/NUKR.CLG 984
2012-2015 Development of nanostructures for target drug delivery into cells with
phagocytic activity – therapy of leukemia” (Academy of Science, Ukraine).Collaboration with the Institute of Molecular Biology and Genetics
2017-2018 Physical mechanisms of oxygen excitation in nanosystems for medical application”(Academy of Science and Ministry of Education, Ukraine)
Novel Hybrid Nanocomposites  for light-triggered and medicamental antitumor therapy” (State Fund for Fundamental Research of Ukraine)
Design and physico-chemical properties of novel multicomponent nanosystems for the treatment and diagnostics of solid tumors” Ukrainian-Republic of Belarus project

Plasmon hybrid nanosystems "metal-polymer-fluorophore" with enhanced optical response for photonics and biomedical Applications. Project. 2020.02/0022. (National Research Foundation of Ukraine)
2022 French program PAUSE (emergency welcome break program for Ukrainian scientists)

2002-2003 Post doctoral fellow (From 1st June until 31th December): Institut Charles Sadron, 
Strasbourg, France, Dr. J.-M. Guenet
2004-2008 Institut Charles Sadron, Strasbourg, France (1-3  months per year), Dr. J.-M. Guenet
2011-2012 Institut Charles Sadron, Strasbourg, France (1 month per year), Dr. M. Rawiso
2015 Contract, Project “Polyelectrolyes in ionic liquids”, Dr. M.Rawiso, Institute Charles Sadron, France (19.01.2015-19.02.2015).
2016 Grant for Scientific training for advanced scientists (French Embassy of Ukraine)
2017 Erasmus Plus Program, Strasbourg University, Faculty of Chemistry and Faculty of Physics
2019 Erasmus Plus Program, Strasbourg University, Faculty of Chemistry and Faculty of Physics

Other Activities
2011-2012 International Scientific Committee of the International IUPAC Conference
on Polymer-Solvent Complexes and Intercalates  “POLYSOLVAT” and Head of the
Organizing Committee from Department of Chemistry for “POLYSOLVAT 9” (11-14
 September 2012, Kyiv)
2013 Invited lecturer, Workshop NATO-Ukraine, 9th November, Kharkiv, Ukraine
2013 Invited lecturer, International scientific school “Polymers in medicine”, 27th May-1st June, Kazan, Russia
2013 Invited lecturer, International scientific school “Macromolecular chemistry”, 23-27th 
December,    Kazan, Russia
2016; 2018 Co-chairmen and Chairmen  of the 10 and 11-th International Conference «Electronic processes in organic and inorganic materials» (ICEPOM–10),
2016- till  now
Responsible for Erasmus Plus program for academic mobility between Taras Shevchenko national University and Strasbourg University (Faculties of Chemistry)
2018 The member of  the Expert commission: 10.04.2018, Institute of Scintillation Materials 
2018 Invited lecturer, International Scholl for Young Scientists “Functional Materials for        
Technical and Biomedial Application”, Kharkiv, 5-8 of September
2018 Invited  lecturer, Scientific and Practical Conference “Application of lasers in medicine  
and biology and 2nd Gamaleia’s Readings. 3-7 October 2018, Haiduszoboslo, Hungary
2019 Invited lecturer, The 1st Symposium of China-Ukraine NanoCarbon Black Joint Researcher Centre, Guangxi, Yulin. China, March 3-10, 2019.
2019 Administrative manager of Common Master programs “Physical Chemistry and materials” and “PopyS” between Taras Shevchenko            
National University and Strasbourg University (Faculties of Chemistry and Physics)

Member of the Editorial board of the Journal “Functional materials” (Scopus)

Methodological and Technical Expertise

  • Chemical modeling of branched polymers
  • Synthesis of nanosystems into polymer matrices
  • All experimental approaches for  characterization of polymers of complicated internal structure and nanosystems: elastic and quasy elastic light scattering, size-exclusion chromatography, transmission electron microscopy, differential scanning calorimetry, viscometry, potentiometric titration etc.
  • VIS, VIS-IR and VIS-UV optical spectroscopy (absorption, reflection, diffuse reflection, photoluminescence, Raman scattering).
  • Optical microscopy.
  • Scanning electron microscopy.
  • Atomic force microscopy.
  • Optical spectroscopy of inorganic, organic and biological systems.
  • Optical measurements in wide range of temperature – from extremely low (1.3 K) to high (1500 K) temperatures.
The team:


PhD V. Chumachenko

PhD Yu. Kuziv

PhD O. Nadtoka

PhD  V.Smokal


PhD P.Virych


Dr.Sci. O.Yeshchenko

Selected Publications

1.    V. Chumachenko, N. Kutsevol, Yu. Harahuts, M. Rawiso, A. Marinin, L. Bulavin. Star-like Dextran-graft-PNiPAM copolymers. Effect of internal molecular structure on the phase transition. Journal of Molecular Liquids. 2017. V.235, P.77-82. (Q1)

2.    N. Kutsevol, A. Glamazda, Chumachenko,Yu. Harahuts, S. G. Stepanian, A. M. Plokhotnichenko, V. A. Karachevtsev. Behavior of hybrid thermosensitive nanosystem dextran-graft-pnipam/gold nanoparticles: characterization within LCTS. Journal of Nanoparticle Research.2018.  J Nanopart Res (2018) 20: 236.(Q2)

3.    Tatiana Matvienko, Viktoriya Sokolova, Svitlana Prylutska, Yuliia Harahuts, Nataliya Kutsevol, Viktor Kostjukov, Maxim Evstigneev, Yuriy Prylutskyy, Matthias Epple, Uwe Ritter. In vitro study of the anticancer activity of various Doxorubicin-containing dispersions. Bioimpacts. 2019;9(1):59-70. (Q1)

4. N. Kutsevol, A. Naumenko, Yu. Harahuts, V. Chumachenko, I. Shton, E. Shishko, N. Lukianova, V. Chekhun. New hybrid composites for photodynamic therapy: synthesis, characterization and biological study.  Appl Nanoscience. 2019. 9: 881. (Q2)

5. Kutsevol, N., Kuziv, Y., Bezugla, T., Andrii Marynin, Natalia Lukianova, Vasyl Chekhun. Application of new multicomponent nanosystems for overcoming doxorubicin resistance in breast cancer therapyAppl Nanosci (2021). (Q2)

6.Oksana Nadtoka, Pavlo Virych, Tetiana Bezugla, Volodymyr Doroschuk, Sergiy Lelyushok, Vadym Pavlenko, Îleg Yeshchenko, Nataliya Kutsevol. Antibacterial Hybrid Hydrogels Loaded with Nano Silver. Appl Nanosci . (2021) (Q2 )

7.Yeshchenko, O.A., Khort, P.S., Kutsevol, N.V. , Prokopets, Vadym; Kapush, Olga; Dzhagan, Volodymyr. Temperature Driven Plasmon-Exciton Coupling in Thermoresponsive Dextran-Graft-PNIPAM/Au Nanoparticle/CdTe Quantum Dots Hybrid NanosystemPlasmonics (2021). (Q2)

8.Nataliya Kutsevol, Yuliia Kuziv, Tristan Cabrera, Valery Bliznyuk, Scott M. Husson, Timothy DeVol. Biodegradable star-like polymer flocculants for rapid, efficient purification of water contaminated with industrial radionuclides. Separation and Purification Technology. Volum 273, 2021, 118630. (Q1)

9.Mariia Chernykh, Dmytro Zavalny, Viktoriya Sokolova, Stanislav Ponomarenko, Svitlana Prylutska, Yuliia Kuziv, Vasyl Chumachenko, Andrii Marynin, Nataliya Kutsevol, Matthias Epple, Uwe Ritter, Jacek Piosik, and Yuriy Prylutskyy. A new water-soluble thermosensitive star-like copolymer as a promising carrier of the chemotherapeutic drug doxorubicin. Materials. 2021. 14(13), P.3517. ( Q2)

10. O.Yeshchenko, N. Kutsevol, A. Tomchuk, P. Khort, P.Virych, V. Chumachenko, Yu. Kuziv, A. Naumenko, A. Marinin. Plasmonic enhancement of the antibacterial photodynamic efficiency of a zinc tetraphenylporphyrin photosensitizer/dextran graft polyacrylamide anionic copolymer/Au nanoparticles hybrid nanosystem. RSC Adv., 2022,12, 13074-13086. (Q1)



ORCID: 0000-0002-1468-4111

Research Gate: Nataliya Kutsevol

Scopus ID: 6603211250

Researcher ID F-1754-2017

Tel: +380503842546,

Research Gate: